Insulin can only be received via injection and cannot be taken orally.
Diabetes: all you need to know about insulin injections
The insulin preparations currently available in Singapore are mostly from human origin; pork or bovine insulin preparations are hardly used nowadays. Because insulin is digested and destroyed by the stomach, it cannot be taken orally. Currently, the only way to receive insulin is by injection. Insulin should only be used when prescribed by a doctor and dose adjustments should be supervised.
There are several types of insulin preparations available: They differ mainly in their onset and duration of action. The rapid and short-acting ones are used mainly to control high blood sugar levels after each meal whilst the intermediate and long-acting ones provide the patients with a smoother day long glucose control.
| Types of Insulin Preparations | Onset of Action | Duration of Action |
|---|---|---|
| Rapid-acting | 15 min | 4 hours |
| Short-acting | 1/2 - 1 hour | 6 - 8 hours |
| Intermediate-acting | 2-4 hours | 16 - 18 hours |
| Long-acting | 4 - 8 hours | 24 hours |
| Premixed insulin | 1/2 - 1 hour | 16 - 18 hours |
Insulin should be given as instructed by the nurse or the pharmacist. The insulin preparations are available in vials, cartridges or penfills and disposable pens. The main precaution the patient needs to be aware of is the risk of developing low blood sugar levels. Low blood sugar levels may happen when the patient is not eating well, taking alcohol on an empty stomach or due to some drug interactions.
How to draw insulin

1. Wash and dry your hands.
2. Clean the rubber stopper on the insulin vial with an alcohol swab.
3. Roll the insulin vial gently between the palms your hand. This provides the dual benefit of mixing the insulin and warming it to body temperature to reduce pain when injecting.

4. Take the syringe from the packet and remove the cap.
5. Draw in air equal to the dose of insulin by pulling the plunger down.
6. With the vial standing upright, insert the needle into the rubber stopper on the vial and push the plunger down. This pushes air into the vial, which makes it easier when withdrawing the insulin out of the vial.
7. Turn the vial and syringe upside down. Slowly pull the plunger down about 5 units past the required dose. If there are no bubbles, push the top of the plunger tip up to the line, which marks the exact dose. If air bubbles are in the syringe, remove them by flicking or tapping the syringe at the bubble with your finger. When the air bubbles rise to the top of the syringe, push the plunger tip up to the exact dose. It is important to get the air bubbles out of the syringe so that you have an accurate dose of insulin.
8. Remove the syringe from the vial.You are now ready to give the injection.

1. Wash and dry your hands.
2. Clean the rubber stopper on the insulin vial with an alcohol swab.
3. Roll the insulin vial gently between the palms of your hand. This provides the dual benefit of mixing the insulin and warming it to body temperature to reduce pain when injecting.

4. Remove the coloured cap of a new vial.Take the syringe from the packet and remove the cap.
5. Draw in air equal to the dose of the cloudy insulin by pulling the plunger down.
6. Insert the needle in the cloudy insulin and inject air into the vial. Do not draw out the cloudy insulin yet. Take the empty syringe out of the cloudy insulin vial.
7. Draw in air equal to the dose of clear insulin.
8. Insert needle into the clear insulin and inject air.
9. Turn the vial of clear insulin and syringe upside down and draw out exact dose.
10. Insert the needle into the vial of cloudy insulin. (Do not push in plunger as this would inject clear insulin into cloudy insulin vial.) To avoid air bubbles, slowly pull back plunger to the exact unit marker for the total dose of clear and cloudy insulin units prescribed.
11. Remove the syringe from the vial. You are now ready to give the injection.
How to select an injection site and inject

How to store insulin vials
Ref: S13
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