An often underdiagnosed and serious condition, Transthyretin Amyloid Cardiomyopathy (ATTR-CM) can result in debilitating symptoms that may lead to death. Studies have shown that the average survival of patients after diagnosis of this heart disease is between three to five years. 

ATTR-CM is caused by an abnormal deposition of proteins on the heart muscles. This protein, called transthyretin (TTR), is normally produced by the liver, and helps to transport the thyroid hormone and vitamin A in the blood. When the abnormal form of the TTR protein accumulates on the heart muscles, it can result in ATTR-CM.

Click here for the full article.


The Straits Times © Singapore Press Holdings Limited. Permission required for reproduction.