HealthXchange will NEVER ask you to transfer money over a call. If in doubt, call the 24/7 ScamShield helpline at 1799, or visit the ScamShield website at www.scamshield.gov.sg.

​Knee Osteoarthritis (OA Knee) Treatment: Medication

Paracetamol ​is one of the common medication used to treat knee osteoarthritis (OA knee).

​Information is provided by the Department of Orthopaedic Surgery at Singapore General Hospital (SGH), a member of the SingHealth group.

Medication to treat knee osteoarthritis (OA knee)​

Diclofenac

Purpose: Relieve pain and reduce swelling or inflammation

Common side effects: Stomach pain/heartburn, upset stomach or nausea, signs of bleeding like throwing up blood or vomitus that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; unexplained bruising or bruising that gets bigger; or any excessive or uncontrollable bleeding (rare, but potentially dangerous)

Glucosamine

Purpose: Help lessen osteoarthritic pain and keep cartilage healthy

Common side effects: Stomach gas (bloating gas), nausea

Naproxen

Purpose: Relieve pain and reduce swelling or inflammation

Common side effects: Stomach pain/heartburn, upset stomach or nausea, signs of bleeding like throwing up blood or vomitus that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; unexplained bruising or bruising that gets bigger; or any excessive or uncontrollable bleeding (rare, but potentially dangerous)

Paracetamol

Purpose: Relieve pain

Common side effects: Skin rash, hypersensitivity reaction (rare)

Because #healthiswealth #healthforgood

Ref: L20

Other osteoarthritis articles you may be interested in:

Osteoarthritis: What You Need to Know

Osteoarthritis Prevention: What You Can Do 

Related Articles

Public Events

18 Nov 2025
Talks Health Talk: How to Eat Healthier during Christmas @ SHP-Outram
​Free, no registration required. Please walk in to clinic at specified date and time. Learn More
20 Nov 2025
Public Blood Donation Drive 2025
Free admission Learn More
20 Nov 2025
Talks Health Talk: Healthy Beverages & Hypoglycemia Management @ SHP-Marine Parade
​Free, no registration required. Please walk in to clinic at specified date and time. Learn More
21 Nov 2025
Others SKH Clean & Green Day